Conveniently located in the heart of the downtown district, the Holiday Inn Mannheim City Centre is among the more well-placed hotels in Mannheim. It is just steps from such sites and attractions as the Congress Center Rosengarten, Wasserturm (water tower), National Theater, major shopping districts, Luisenpark, and Mannheim's Palace. The Holiday Inn Mannheim City Centre is located at Kurfuersten Arkade, N 6 D-68161, and is within a mile from Mannheim City Airport or the Hauptbahnof Railway Station.

All 146 guestrooms in the Holiday Inn Mannheim City Centre will come equipped with high-speed Internet access, air conditioning, a minibar, satellite TV, and a large private bathroom. Deluxe Rooms also feature tea/coffee making facilities, a personal safe, an additional seating area and extensive desk with ergonomic chair.

Guests of the Holiday Inn Mannheim City Centre will be able to enjoy amenities and services that include banqueting facilities, a currency exchange, a modern fitness room, laundry and dry cleaning services, public parking on the premises, a business center, meeting and conference rooms, an in-house restaurant, 24-hour front desk service, a lounge with bar service, golf course in the vicinity (10 km), a news stand, pet friendly policies, and a swimming pool.